Investigation of extraesophageal gastroesophageal reflux disease

نویسندگان

  • Emmanouela Tsoukali
  • Daniel Sifrim
چکیده

The most common extraesophageal manifestations of gastroesophageal reflux disease (GERD) include chronic cough, asthma and laryngitis. There are two mechanisms proposed to explain extraesophageal syndromes caused by GERD. The first one is a direct way via irritation and/or microaspiration and the second one is an indirect, vagally mediated way. The investigation of extraesophageal manifestations of GERD is difficult and the empirical therapy with proton pump inhibitors usually double dose for at least three months is still the most common approach.

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عنوان ژورنال:

دوره 26  شماره 

صفحات  -

تاریخ انتشار 2013